Search results for "Glucose utilization"
showing 4 items of 4 documents
The pancreatic beta-cell response to intravenous administration of glucose in elderly subjects.
1970
A study was made of the serum insulin level after the intravenous administration of glucose (0.33 gm/ kg) in two groups of normal subjects—18 in the 60–85 age bracket, and 16 in the 23–45 age bracket. All had a normal coefficient of glucose utilization and a normal blood glucose curve after intravenous administration of glucose. Serum insulin was assayed by the radio-immunological method, with use of an ion exchange resin. Blood samples were drawn at 2, 5, 10, 30, 45 and 60 minutes after the end of the glucose infusion. In the elderly subjects the maximal value was reached only after 5 minutes and the mean value was 39± 9 µU/ml (range, 27–50), whereas in the younger subjects the serum insul…
Utilization of glucose and proline in the brain of adult insects
1986
Abstract The objective of this study was to ascertain if proline can be used as a substrate by insect brains. Utilization of d -[U14C]glucose and l -[U14C]proline by isolated brains from 25 different species of insects, belonging to six separate orders, was measured using a radiomicrorespirometric method. Glucose utilization is more pronounced in brains of relatively smaller and highly evolved insects than in larger and more primitive insects. Brains of Blattodea exhibit little proline utilization. 14CO2 production from labelled glucose and proline in brains of insects seems to be correlated with the metabolic rate of these organs.
Glucose, Lactate, and Ketone Body Utilization by Human Mammary Carcinomas in Vivo
1985
Uncontrolled growth, one of the fundamental properties of malignant tumors, requires a great supply of energy. This energy can be derived from the use of a variety of substrates. Besides glucose oxidation and glucose breakdown to lactic acid, the turnover of endogeneous substrates such as amino acids, free fatty acids and ketone bodies is well documented in vitro. However, under in vivo conditions, only glucose utilization has been investigated in detail, using tumor isotransplants in rodents. For human tumors, only scarce data is available, derived mainly from clinical observations rather than from systematic studies.
The Effects of Self-Control on Glucose Utilization in a Hyperinsulinemic Euglycemic Glucose Clamp
2019
Abstract. Background. The glucose hypothesis of self-control posits that acts of self-control may draw upon glucose as a source of energy, leading to a decrease in blood glucose levels after exerting self-control, mirroring the temporary depletion of self-control, but supporting evidence is mixed and inconclusive. This might partly be due to using methods that are not suitable to reliably quantify glucose utilization. Aims. We aimed at examining whether self-control exertion leads to an increase in glucose utilization. Method. In a sample of N = 30 healthy participants (50% women, age 26.5 ± 3.5 years) we combined a hyperinsulinemic euglycemic glucose clamp (a well-established and validate…